Mechanism of action

Dicot Pharma is characterizing the mechanism of action of LIB-01. It’s now known that LIB-01 affects underlying structures that play a central role in penile erection.

A penile erection occurs in response to sexual stimulation where a dramatic increase in arterial inflow to the penis is essential and must be accompanied by a relaxation of the erectile tissue. Everything is under neural command. By analyzing gene expressions* in anatomical structures involved in penile erection, it has been found that LIB-01 affects the nervous and vascular structures that are involved in these processes.

This differentiates LIB-01 from today's potency drugs. It demonstrates the potential to change the paradigm of erectile dysfunction management and supports our goal to also offer treatment for men who are not currently helped by PDE5 inhibitors.

The change in gene expression may also explain LIB-01´s long-lasting effect on erectile function.

*Gene expression is a naturally occurring process whereby information from genes is transferred to the cell's structures and functions, and the effects can be long-lasting.